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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0423689b6d0065c96ae4f1125de7b61161bb2956471e701ff2d1c2968667b3a3' 
  AND token = 'VqTN3wMbP7G2p6WmlbDyH7M02WsqUEA1Uwot5CUHeQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}