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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6222748cc7a33ae9be8de86c6227a6d6ab996bf6faeaee9f6b0cf6389dc423a4' 
  AND token = 'EO3dWc+6kA4BGTBNVD/+s8lr1mOgevmKm2/Nyo3GWQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}