SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '503fb437da5ca86a62c4900621c57518e12bbe280037b01e1df306157bc006bd' 
  AND token = 'HkYNNmj5CdZBt34/8tJxJGSUMnVDd9+gX7PPVo1xHvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}