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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f61563dc328465578721ed0332d43cc9e971223ec77c9015245984e53298aa1' 
  AND token = '1+XYACbbI/L9zYNldDghf5fGzazO5rACcmT0kz63Buw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}