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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4057d8ac6ada860dc72474eb2623be5f331216be50d1023d6da3bff74709f12' 
  AND token = '9hBQStiXjhiRwn1EQI8DQUxwDW0NV07zEXsQ99T94wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}