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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '135e8200e80a653f65dd65539cd815d738fc6e35644c3e99a33494d6ce38a5a6' 
  AND token = '0AXZgrFJjXdLBrobQw7XqJHE5vyXFcCMtPxm7xJLtTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}