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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0bd7cae975bb821d1282e89d8272ce7d463ae6284e3f06b9f507c389c56a420' 
  AND token = 'Tx3fT6VUR/68KtY/gjDLBsino95brZwzn20I2nhZn6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}