SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd06ec97644dfabfe9e16523a3f42c00f21d6ac531f96908063ab24913b5f5138' 
  AND token = 'PAcrmfzWy9lFayMKB6X+NcAsal1XZgXhPAxVdMAJgLw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}