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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '200261e5d17e4cc87058b8fe03ddbb53439903861c6f306f2242a7cbd13a351e' 
  AND token = 'eiyeTP3srzIxlvLTSidpni/DAXafqcJKPyZH3uCChR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}