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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e190f7bbb2c3f60b64fb7798dc85e40d9719feb1dfe9fe257d7cff3a77a138' 
  AND token = 'ag87NIzsa1oxYdMKHW8s4IVHyWj3kUA+pJ2DgvzFsxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}