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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf5a8e005c7036040592ad8304f6f4698a7a16f25c7399f0a2c7ddd5e7b1d164' 
  AND token = 'O5E0I5USIRRIW33j1TcyM5a6F5YX8yYmU53FTwJ71FY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}