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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9414c7be57d0d480d311a1e42c5e23630e50f99e16c97043ce5818d722cf6700' 
  AND token = 'xnMCreMWy1t2qeUjEiwuFTPUZvKX1m7F+Qh8FtSx9cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}