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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd22603dccb4d440eb9c592aca31e59f5aafb2f553dd32f457e843746ced8b482' 
  AND token = '8xXEOfwGpSEtqtDCyteeAsYZbcv+DpjeJnHsbeieO9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}