SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd73b17eef55c80da3e8dac5a0a9e5560161c95ee869c70447be36a7290a46c' 
  AND token = 'kKxwjWLEFeLcFPpYoQRyc/PcEl/LPsIl4ADlDs7ZHGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}