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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa2b01c93b6e9448f92c42965203d54bc4876edd9979e5b3f2ecaa14f9563bcb' 
  AND token = '7C48wwT06k6T0au3TSHlhFdNBp7kNKUHWjVg1HaHXGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}