SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8df4319a5896429dc573d03fca00b17e8100827aac6b373b4cd014d21ea77e60' 
  AND token = 'KUybGw6SdvibdD3gHiXt+313PHYISmCFoI9TsfXakEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}