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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6956b533eb9327d8e7ec1a0b78d706e374f7241478286e6583b1f5670307498' 
  AND token = 'UPh8YdSLpnxIWOzUANJh0zC3hxCbB4Ex2VDaQBucMYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}