SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286855687b4fd662cb17870e74c05710080fbf0dcf896d3b59393c489ed28009' 
  AND token = 'QcbDazMPFQiwtxoxK59P8xjDi+7ZmfD++66yFmT4TzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}