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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d2788cde03a033b44b0c562511106c2ec57809496b2cf6b7ecc407e082f3c63' 
  AND token = 'HcSDrUmLShEf4CaXhxNiTc1wITgqtOSsxNXikcCXfFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}