SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c694c448c1aa715cb2a0d2f07189a081e13169bbc115e2fc95bd2da33d4320c' 
  AND token = '5zwBlGJHf+3GszmICIa3/wSN5dOmkatLJJDr8n5NfIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}