SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f245f71c85923f28f33166e319072a2b1d5152bf7ede45b38cfbd1a4b9098ce3' 
  AND token = 'Kh5A2jFddFZJrGtqfu1w2f6y3j/eE/aGMaFnfSoMyCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}