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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '008509d1eb66abc1048479f74547c9c933cc34f67482b3a8a82102c199fc8b46' 
  AND token = 'FSJIn4YCUB5RNznSlCF4rec6U1dUU8iqhKycN9yBqBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}