SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fded46d100323db52acd17b979fd43f909551a96cb30ca49b2239b89941acfc' 
  AND token = '6UYl4Wuddb1GucW3RLoEzuDbAjAroAtoMGk5LwTi20o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}