SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74fd0a1267cdf3c0ea3a398425fddf699dc167305de2b8a9a1beb80021ac8e22' 
  AND token = 'HHf/mcgETD9PcNUIix9mEPJrJAd55XdINrx+zZhX1OA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}