SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05f0a4e16eae716c69b68da912bc212148dafd9771f2f93c26b675387543148c' 
  AND token = 'BJtOVhPI4SWcGbVgGhRzCP+FWj5Dbas9LxanFxsma4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}