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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae26438282492676d314c83d120cc78c1fac5a4b9c13b473403a32ea517bbdf9' 
  AND token = 'vtrr4T/BMOpThaDqh4uZLTixleiLJdLVDgMKz10nO/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}