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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '460a90f9cac18f1fa8accbe736dbd1c408add9d225313970fdb50722d8a7d3ad' 
  AND token = '4vYuJ8hOQCCXye69p2fAv+H+6otqHHe5xb6Z3hWNVN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}