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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3f6b29447332667a5dbc260eb99e7545e2e401b59b296b4e91e55cc434b1bda' 
  AND token = 'EqGXPMAmMu5Xth60TD9I78xB9RtDlSHPAOirMoDokaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}