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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37dfde6e481df612101ae11357253a62a4d1a74c09dab18018b7502a240b03a4' 
  AND token = 'v37PY10fbI7Tp6ZgCVBSKpilnADt+Ee1RiwPfmxxoZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}