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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f781864908d31b8b2a9316e2f06520bdaa99957392a18d5f11ce8a82f44a6eb' 
  AND token = 'j/Qx1lMj6JaqOvxhfLXONl7yDQcg7CJ1QaEtmKNYd4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}