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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022bc4c97d516a9d5528aba72761c9fc304e854939f95814728173f64b7ffff5' 
  AND token = 'U3pNfXgACgJgG67c6oaNrivqo8c1asYCN35YyOZbn9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}