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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ff46c2acae2db7ce89fdd8b8fb557a4c71282a81f0bef1616b19b3bb00d32e' 
  AND token = 'iO1rcjYDLr7EExrXC0Lw8qODsC8DF7NhhwBQHXYy9M4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}