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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f77ae728aa424e552b71a08ec344e40d2951e870b19f8e9d06ade8d9cac1d9' 
  AND token = 'bl1cGV9yetrm3ZmeJ/XB1XVKdvIc28spKrgLWGChrcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}