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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed06fbc50dc5b7d7fd56bf902b1bd2ca9cb1e359691f21e141276532f5d5962' 
  AND token = '8KmlgnTgfLCHE5jX7OQ2ScLXfBw66T4HW9nQ9pkCZtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}