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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2f29f602b44fb6c506aa3b84d0086115ce99683d394ac8e48c0db04db2e9b7' 
  AND token = 'DQmdQcynGmJ+MvpsH4Z7hAyPGc0AI5I1ibVA9ccRrlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}