SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c1896d46e0aef2c20c621182defdc83951db23130a1923e044e48d8c6f9ce03' 
  AND token = 'aVBztUpZgJ1Pdw5avvUjzQSIwwnxW7bhimb6R+bNeIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}