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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb72efe48eb46591bdaf8698cdf4d66d88db14cf056906a6fcdb03c39e0b0fca' 
  AND token = 'AlpqVekvI7RFkt4JGXvlURX9l81is2pI//tZdvMrd90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}