SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b95d370ee8f8783d31f68afd2d22661d805454cbb532b748855a681e4beade0a' 
  AND token = 'RGf5uU+xzaktUkK1/s7iG/vRewgZySN/fP9tAar3ACY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}