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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '090918298e6635a566e3088de32d386d5a6dcd7ecb84a7b1a6e547baee1bfc50' 
  AND token = '3rV30uSMbTC2/PQf6qZrzu7BTJNCJO8zvNAEUoBODHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}