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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1638f5167cf007165d76b1b9ba7a6405b6ff1ca3ec2146b300cbae4368090914' 
  AND token = 'GGa14a0JXdWoJLJ1HclLH86/q9LQ2f8q3dRR0z1tuVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}