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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b5fc6c64329c583ce61a67d4a3f8e0d42b9c5129ed1d9071ac08591a329f899' 
  AND token = '294F21w9RhNVZNnQb0IS48yfo19iYiauER08PVEFLlU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}