SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b610b28f2e68cc4c5d07a1258766a5878e241c0a7f77b5da7993356a52706e5' 
  AND token = 'p8Dff4YEbZwnG232dKLsICANwxgbbcwIBxTNkCTscV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}