SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7095d23dede7603d6d3b81f506f39db01883acbf90f02a1affa67d184df8eed' 
  AND token = 'nkAs7RBF5dCZfE3dz6+22prWIerGHIYlYPaI7hiFIHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}