SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780e4cc2e98d23b50c5c93e325a70861560fcbcf4c8771e7877f26b825cd1c4d' 
  AND token = 'YMVhLEq8GF+zUsnzMz+QbUH5Ih3/99U9zD1mh87k6JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}