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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c959395bd19db782a7afcdd4ab1c4fedc35e85cf86261d172509ae4d243d872' 
  AND token = '6b6pMPJrnSMjEP2AN/BUJptmUWKOzmd+QpfRS/unvIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}