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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bfdad755b51c4caf961edbdebf9d0e5b817d5e46f12c34207813b2c2c576bb2' 
  AND token = 'rD1kwAffN/rYedD9PEoQEL6t7SFWmsQfS7Tp7nU2KIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}