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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e781ad8c0d9b863378d3e31792116aba5c49d219956012d48acb69c3e2c2179' 
  AND token = '+1PXTKbPQee+pqOMyC6CYCTxIdp+ZgCvCSvQWx3y2KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}