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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5c9a108b0a1bcafe951cd17f48ea11185617e2de71a96608c4bafc4c644c378' 
  AND token = 'osAmBD+JTjND+r8MudjOf4sKtoUL5wrFe3H+Xr3qSRY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00099

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}