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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '837de9d19162c9a68c4b9d9155659178a50ec742a570846c144a8d3dc7c021e0' 
  AND token = 'A05wV1Z6+nIDFgAeFUJ3SBIa8utlNKi60zg9pi9Lbqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}