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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b08ca1e78f8ad573fceb6563b6bd74fcff333b4f1af0e427475c15095a4c2a' 
  AND token = 'wUxNp3LIB+7vXe76vbowRpJLDyPrNX4oG7+SA4EJJ9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}